Corticosteroids and multiple sclerosis
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چکیده
منابع مشابه
Corticosteroids and multiple sclerosis.
It is common practice to employ a short course of corticosteroids to treat acute relapses of multiple sclerosis. Two approaches, high dose intravenous methylpred-nisolone (IVMP) and intramuscular ACTH, have been shown when compared to placebo to shorten the duration of relapses, 1 2 although there is no evidence that the final outcome is changed. Of these, IVMP has become the more popular, bein...
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While recognizing that the factors that enter into a decision to treat are complex and best analyzed by the individual patient’s neurologist, the National Clinical Advisory Board of the National Multiple Sclerosis Society has adopted the following recommendations to provide guidance to clinicians, insurers, and policy-makers regarding the appropriate use of corticosteroids in the management of ...
متن کاملCorticosteroids for the long-term treatment in multiple sclerosis.
BACKGROUND Short term high dose corticosteroid treatment improves symptoms and short term disability after an acute exacerbation of multiple sclerosis (MS) but it is unknown whether its long-term use can reduce the accumulation of disability. OBJECTIVES To determine the efficacy and safety of long-term corticosteroid use in MS. SEARCH STRATEGY We searched the following bibliographic databas...
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Multiple sclerosis (MS) is an inflammatory and autoimmune disease.MS is characterized by blood brain barrier breakdown, inflammation, axonal injury, degeneration of the myelin sheath and etc. A significant association between inflammation and degeneration of neurons is observed in the brain. Also active MS lesions always associated with inflammation thus inflammation is a target for treatment o...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1998
ISSN: 0022-3050
DOI: 10.1136/jnnp.65.3.290